When a organism starts to create extra movement within their body, they heart has to pump oxygen into the parts of the body to move. The main body parts would be the muscle system. When a person goes to lift a weight, the muscle is being flooded with oxygen to be able to handle to the load. However, when bodybuilding or lifting, the muscle it also being destroyed. That is why the muscles get bigger every time we work out. The muscle now knows that in order to do that again it must regenerate larger and stronger than before. That is what causes the feeling of soreness. However getting the topic, when a muscle group is being used, oxygen floods that muscle to keep it working. When a runner does a sprint, their quads are being used heavily and the muscle is being torn apart. Because of the excess blood flow to the muscle. The oxygen is no longer circulating through the lungs, which cause being out of breath, because literally the lungs are.